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Rapid Aging in the Perforant Path Projections to the Rodent Dentate Gyrus

Why layers II/III of entorhinal cortex (EC) deteriorate in advance of other regions during the earliest stages of Alzheimer's disease is poorly understood. Failure of retrograde trophic support from synapses to cell bodies is a common cause of neuronal atrophy, and we accordingly tested for ear...

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Publicado en:J Neurosci
Main Authors: Amani, Mohammad, Lauterborn, Julie C., Le, Aliza A., Cox, Brittney M., Wang, Weisheng, Quintanilla, Julian, Cox, Conor D., Gall, Christine M., Lynch, Gary
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018768/
https://ncbi.nlm.nih.gov/pubmed/33514675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2376-20.2021
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