Orexin-A Intensifies Mouse Pupillary Light Response by Modulating Intrinsically Photosensitive Retinal Ganglion Cells

We show for the first time that the neuropeptide orexin modulates pupillary light response, a non-image-forming visual function, in mice of either sex. Intravitreal injection of the orexin receptor (OXR) antagonist TCS1102 and orexin-A reduced and enhanced pupillary constriction in response to light...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Wei, Wang, Li-Qin, Shao, Yu-Qi, Han, Xu, Yu, Chen-Xi, Yuan, Fei, Wang, Xin, Weng, Shi-Jun, Zhong, Yong-Mei, Yang, Xiong-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018734/
https://ncbi.nlm.nih.gov/pubmed/33536197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0217-20.2021
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