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Implicit ligand theory for relative binding free energies: II. An estimator based on control variates

Implicit ligand theory describes the relationship between the noncovalent binding free energy and the binding free energy between a ligand and multiple rigid receptor conformations. We have previously shown that if the receptor conformations are sampled from or reweighed to a holo ensemble, the bind...

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Xehetasun bibliografikoak
Argitaratua izan da:J Phys Commun
Egile Nagusiak: Nguyen, Trung Hai, Minh, David D. L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018686/
https://ncbi.nlm.nih.gov/pubmed/33817346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2399-6528/abcbac
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