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Impact of ETNK1 somatic mutations on phosphoethanolamine synthesis, ROS production and DNA damage

Recently we showed that Ethanolamine Kinase 1 (ETNK1) mutations cause a decreased synthesis of phosphoethanolamine, and that phosphoethanolamine is able to modulate mitochondrial activity through competition with succinate for complex II. The decreased phosphoethanolamine concentration leads to incr...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Fontana, Diletta, Gambacorti-Passerini, Carlo, Piazza, Rocco
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018496/
https://ncbi.nlm.nih.gov/pubmed/33860081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1877598
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