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P53 regulates cellular redox state, ferroptosis and metabolism

The tumor protein P53 (TP53, or p53) has complex and at times seemingly contradictory roles in the regulation of metabolism and ferroptosis sensitivity. We find that the actions of p53 influence the redox state, which can trigger changes in redox-sensitive proteins, thereby modifying metabolic proce...

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Publicat a:Mol Cell Oncol
Autors principals: Leu, Julia I-Ju, Murphy, Maureen E., George, Donna L.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018455/
https://ncbi.nlm.nih.gov/pubmed/33860080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1877076
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