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A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs
While Janus-kinase (JAK)-inhibitors effectively reduce the inflammatory phenotype of myeloproliferative neoplasms (MPN), they do not affect disease burden or presence of the mutated clone to a major extent. Here, we show how Janus-kinase 2 (JAK2)-mutated cells persist through maintenance of the mito...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8018336/ https://ncbi.nlm.nih.gov/pubmed/33855167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1871172 |
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