A Phase Ib Study of NUC‐1031 in Combination with Cisplatin for the First‐Line Treatment of Patients with Advanced Biliary Tract Cancer (ABC‐08)

BACKGROUND: Cisplatin/gemcitabine is standard first‐line treatment for patients with advanced biliary tract cancer (ABC). NUC‐1031 (phosphoramidate transformation of gemcitabine) is designed to enhance efficacy by maximizing intratumoral active metabolites. METHODS: Patients with untreated ABC, East...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncologist
Auteurs principaux: McNamara, Mairéad G., Bridgewater, John, Palmer, Daniel H., Faluyi, Olusola, Wasan, Harpreet, Patel, Alkesh, Ryder, William D., Barber, Safia, Gnanaranjan, Chathunissa, Ghazaly, Essam, Evans, T.R. Jeff, Valle, Juan W.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2020
Sujets:
Hepatobiliary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018303/
https://ncbi.nlm.nih.gov/pubmed/33210382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/onco.13598
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