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Sequestosome‐1 (p62) expression reveals chaperone‐assisted selective autophagy in immune‐mediated necrotizing myopathies

Diffuse myofiber necrosis in the context of inflammatory myopathy is the hallmark of immune‐mediated necrotizing myopathy (IMNM). We have previously shown that skeletal muscle fibers of IMNM patients may display nonrimmed vacuoles and sarcoplasmic irregularities. The dysfunctional chaperone activity...

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Podrobná bibliografie
Vydáno v:Brain Pathol
Hlavní autoři: Fischer, Norina, Preuße, Corinna, Radke, Josefine, Pehl, Debora, Allenbach, Yves, Schneider, Udo, Feist, Eugen, von Casteleyn, Vincent, Hahn, Katrin, Ruck, Tobias, Meuth, Sven G., Goebel, Hans‐Hilmar, Graf, Rose, Mammen, Andrew, Benveniste, Olivier, Stenzel, Werner
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018061/
https://ncbi.nlm.nih.gov/pubmed/31376301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12772
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