PD1 pathway in immune-mediated myopathies: Pathogenesis of dysfunctional T cells revisited

OBJECTIVE: To investigate the relevance of dysfunctional T cells in immune-mediated myopathies. We analyzed T-cell exhaustion and senescence, in the context of programmed cell death protein 1 (PD1)-related immunity in skeletal muscle biopsies from patients with immune-mediated necrotizing myopathy (...

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Publicat a:Neurol Neuroimmunol Neuroinflamm
Autors principals: Knauss, Samuel, Preusse, Corinna, Allenbach, Yves, Leonard-Louis, Sarah, Touat, Mehdi, Fischer, Norina, Radbruch, Helena, Mothes, Ronja, Matyash, Vitali, Böhmerle, Wolfgang, Endres, Matthias, Goebel, Hans-Hilmar, Benveniste, Olivier, Stenzel, Werner
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467687/
https://ncbi.nlm.nih.gov/pubmed/31044146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000558
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