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Applying gene‐editing technology to elucidate the functional consequence of genetic and epigenetic variation in Alzheimer’s disease

Recent studies have highlighted a potential role of genetic and epigenetic variation in the development of Alzheimer’s disease. Application of the CRISPR‐Cas genome‐editing platform has enabled investigation of the functional impact that Alzheimer’s disease‐associated gene mutations have on gene exp...

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Publicat a:Brain Pathol
Autors principals: Schrauben, Michael, Dempster, Emma, Lunnon, Katie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018012/
https://ncbi.nlm.nih.gov/pubmed/32654206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12881
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