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An autism-associated calcium channel variant causes defects in neuronal polarity in the ALM neuron of C. elegans

Variants of the CACNA1C voltage-gated calcium channel gene have been associated with autism and other neurodevelopmental disorders including bipolar disorder, schizophrenia, and ADHD. The Timothy syndrome mutation is a rare de novo gain-of-function variant in CACNA1C that causes autism with high pen...

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Библиографические подробности
Опубликовано в: :MicroPubl Biol
Главные авторы: Buddell, Tyler, Quinn, Christopher C
Формат: Artigo
Язык:Inglês
Опубликовано: Caltech Library 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017444/
https://ncbi.nlm.nih.gov/pubmed/33829152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17912/micropub.biology.000378
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