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An autism-causing calcium channel variant functions with selective autophagy to alter axon targeting and behavior

Common and rare variants of the CACNA1C voltage-gated calcium channel gene have been associated with autism and other neurodevelopmental disorders including schizophrenia, bipolar disorder and ADHD. However, little is known about how CACNA1C variants affect cellular processes to alter neurodevelopme...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Buddell, Tyler, Friedman, Vladislav, Drozd, Cody J., Quinn, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894750/
https://ncbi.nlm.nih.gov/pubmed/31805042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008488
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