ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant cancers in East Asia, with high incidence and mortality. Accumulating evidence has shown that ATF3 is associated with tumor progression. METHODS: Using qPCR, the expression of ATF3 was detected in 93 patients wit...

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Udgivet i:Front Cell Dev Biol
Main Authors: Gao, Shenglin, Gao, Lei, Wang, Simin, Shi, Xiaokai, Yue, Chuang, Wei, Shuzhang, Zuo, Li, Zhang, Lifeng, Qin, Xihu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017234/
https://ncbi.nlm.nih.gov/pubmed/33816467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.618987
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