Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo

The lack of a non-invasive test for malignant thyroid nodules makes the diagnosis of thyroid cancer (TC) challenging. Human galectin-3 (hGal3) has emerged as a promising target for medical TC imaging and diagnosis because of its exclusive overexpression in malignant thyroid tissues. We previously de...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Peplau, Emanuel, De Rose, Francesco, Eichinger, Andreas, Reder, Sybille, Mittelhäuser, Markus, Scafetta, Giorgia, Schwaiger, Markus, Weber, Wolfgang A., Bartolazzi, Armando, D’Alessandria, Calogero, Skerra, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016950/
https://ncbi.nlm.nih.gov/pubmed/33795750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86641-0
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