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High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides
MOTIVATION: The binding of T-cell receptors (TCRs) to their target peptide MHC (pMHC) ligands initializes the cell-mediated immune response. In autoimmune diseases such as multiple sclerosis, the TCR erroneously recognizes self-peptides as foreign and activates an immune response against healthy cel...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8016493/ https://ncbi.nlm.nih.gov/pubmed/33355667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1050 |
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