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Sparse Project VCF: efficient encoding of population genotype matrices

SUMMARY: Variant Call Format (VCF), the prevailing representation for germline genotypes in population sequencing, suffers rapid size growth as larger cohorts are sequenced and more rare variants are discovered. We present Sparse Project VCF (spVCF), an evolution of VCF with judicious entropy reduct...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Lin, Michael F, Bai, Xiaodong, Salerno, William J, Reid, Jeffrey G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016461/
https://ncbi.nlm.nih.gov/pubmed/33300997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1004
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