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LDpred2: better, faster, stronger
MOTIVATION: Polygenic scores have become a central tool in human genetics research. LDpred is a popular method for deriving polygenic scores based on summary statistics and a matrix of correlation between genetic variants. However, LDpred has limitations that may reduce its predictive performance. R...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8016455/ https://ncbi.nlm.nih.gov/pubmed/33326037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1029 |
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