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LDpred2: better, faster, stronger

MOTIVATION: Polygenic scores have become a central tool in human genetics research. LDpred is a popular method for deriving polygenic scores based on summary statistics and a matrix of correlation between genetic variants. However, LDpred has limitations that may reduce its predictive performance. R...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Privé, Florian, Arbel, Julyan, Vilhjálmsson, Bjarni J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016455/
https://ncbi.nlm.nih.gov/pubmed/33326037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1029
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