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Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through AMPKα-SREBP2 pathway
R-spondins (Rspos) are endogenous ligands of leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4). Rspos-LGR4 signaling plays important roles in embryogenesis, gastrointestinal homeostasis and food intake. Here, we investigated impacts of Rspos-LGR4 on hepatic cholesterol synthesis. Rs...
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| I publikationen: | FASEB J |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8016451/ https://ncbi.nlm.nih.gov/pubmed/32926477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001234R |
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