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R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin

BACKGROUND & AIMS: Leucine-rich repeat G-protein-coupled receptor 4 (LGR4) and its ligands R-spondin1-4 (Rspos) have been vastly investigated in embryonic development. The biological functions of Rspos-LGR4 system in liver remains largely unknown. Here, we explored whether it protects hepatocyte...

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Bibliografiset tiedot
Julkaisussa:Biochem Biophys Res Commun
Päätekijät: Liu, Shiying, Yin, Yue, Yu, Ruili, Li, Yin, Zhang, Weizhen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170193/
https://ncbi.nlm.nih.gov/pubmed/29555474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.03.126
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