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DNA polymerase theta suppresses mitotic crossing over
Polymerase theta-mediated end joining (TMEJ) is a chromosome break repair pathway that is able to rescue the lethality associated with the loss of proteins involved in early steps in homologous recombination (e.g., BRCA1/2). This is due to the ability of polymerase theta (Pol θ) to use resected, 3’...
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| Vydáno v: | PLoS Genet |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8016270/ https://ncbi.nlm.nih.gov/pubmed/33750946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009267 |
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