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RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells

The therapeutic approach of liver fibrosis is still an unsolved clinical problem worldwide. Notably, the accumulation of extracellular matrix (ECM) in the liver is mediated by the production of cytokines and growth factors, such as transforming growth factor-β1 (TGF-β1) in hepatic stellate cells (HS...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Yan, Qi, Pan, Linxin, Qi, Shunli, Liu, Fang, Wang, Zhen, Qian, Cheng, Chen, Lijian, Du, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015948/
https://ncbi.nlm.nih.gov/pubmed/33816485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634902
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