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RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells

The therapeutic approach of liver fibrosis is still an unsolved clinical problem worldwide. Notably, the accumulation of extracellular matrix (ECM) in the liver is mediated by the production of cytokines and growth factors, such as transforming growth factor-β1 (TGF-β1) in hepatic stellate cells (HS...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Yan, Qi, Pan, Linxin, Qi, Shunli, Liu, Fang, Wang, Zhen, Qian, Cheng, Chen, Lijian, Du, Jian
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015948/
https://ncbi.nlm.nih.gov/pubmed/33816485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634902
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