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RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells

The therapeutic approach of liver fibrosis is still an unsolved clinical problem worldwide. Notably, the accumulation of extracellular matrix (ECM) in the liver is mediated by the production of cytokines and growth factors, such as transforming growth factor-β1 (TGF-β1) in hepatic stellate cells (HS...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Yan, Qi, Pan, Linxin, Qi, Shunli, Liu, Fang, Wang, Zhen, Qian, Cheng, Chen, Lijian, Du, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015948/
https://ncbi.nlm.nih.gov/pubmed/33816485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634902
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