In Silico, In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST(4) Receptor Agonists

Background: Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via its receptor subtype 4 (SST(4)) without influencing endocrine functions. Therefore, SST(4) is considered to be a novel target for drug development in pain, especially ch...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Kántás, Boglárka, Szőke, Éva, Börzsei, Rita, Bánhegyi, Péter, Asghar, Junaid, Hudhud, Lina, Steib, Anita, Hunyady, Ágnes, Horváth, Ádám, Kecskés, Angéla, Borbély, Éva, Hetényi, Csaba, Pethő, Gábor, Pintér, Erika, Helyes, Zsuzsanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015869/
https://ncbi.nlm.nih.gov/pubmed/33815096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.601887
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