Nalaganje...

Intra-lacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects Without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is an autoimmune disease associated with severe exocrinopathy, which is characterized by profound lymphocytic infiltration (dacryoadenitis) and loss of function of the tear-producing lacrimal glands (LG). Systemic administration of Rapamycin (Rapa) significantly reduces LG in...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomacromolecules
Main Authors: Ju, Yaping, Edman, Maria C., Guo, Hao, Janga, Srikanth Reddy, Peddi, Santosh, Louie, Stan G., Junge, Jason A., MacKay, J. Andrew, Hamm-Alvarez, Sarah F.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015671/
https://ncbi.nlm.nih.gov/pubmed/33356170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.0c01468
Oznake: Označite
Brez oznak, prvi označite!