Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats

Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovial tissue, joint dysfunction, and damage. Epoxyeicosatrienoic acids (EETs) are endogenous anti-inflammatory compounds, which are quickly converted by the soluble epoxide hydrolase (sEH) enzyme into a less active form wit...

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Pubblicato in:Int Immunopharmacol
Autori principali: Teixeira, Juliana Maia, Abdalla, Henrique Ballassini, Basting, Rosanna Tarkany, Hammock, Bruce D., Napimoga, Marcelo Henrique, Clemente-Napimoga, Juliana Trindade
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015648/
https://ncbi.nlm.nih.gov/pubmed/32736189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2020.106841
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