Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model

Epoxyeicosatrienoic acids (EET) and related epoxy fatty acids (EpFA) are endogenous anti‐inflammatory compounds, which are converted by the soluble epoxide hydrolase (sEH) to dihydroxylethersatrienoic acids (DHETs) with lessened biological effects. Inhibition of sEH is used as a strategy to increase...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Trindade‐da‐Silva, Carlos A., Clemente‐Napimoga, Juliana T., Abdalla, Henrique B., Rosa, Sergio Marcolino, Ueira‐Vieira, Carlos, Morisseau, Christophe, Verri, Waldiceu A., Montalli, Victor Angelo Martins, Hammock, Bruce D., Napimoga, Marcelo H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383812/
https://ncbi.nlm.nih.gov/pubmed/32400048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000415R
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