Clinical Relevance of Anti-TNF Antibody Trough Levels and Anti-Drug Antibodies in Treating Inflammatory Bowel Disease Patients

BACKGROUND AND AIMS: The majority of patients treated with anti-tumor necrosis factor (TNF) therapy develop anti-drug antibodies (ADAs), which might result in loss of treatment efficacy. Strict guidelines on measuring trough levels (TLs) and ADA in clinical routine do not exist. To provide real-worl...

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Udgivet i:Inflamm Intest Dis
Main Authors: Reinhold, Ilana, Blümel, Sena, Schreiner, Jens, Boyman, Onur, Bögeholz, Jan, Cheetham, Marcus, Rogler, Gerhard, Biedermann, Luc, Scharl, Michael
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2021
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015259/
https://ncbi.nlm.nih.gov/pubmed/33850838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000511296
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