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The Efficacy and Safety of Golimumab as Third- or Fourth-Line Anti-TNF Therapy in Patients with Refractory Crohn's Disease: A Case Series

BACKGROUND: The TNF-α antagonist golimumab is approved for the treatment of ulcerative colitis but not for Crohn's disease (CD). We herein report a case series of 8 difficult-to-treat patients with severe and refractory CD receiving golimumab as an off-label rescue medication and fourth-line an...

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Publicado en:Inflamm Intest Dis
Autores principales: Russi, Linda, Scharl, Michael, Rogler, Gerhard, Biedermann, Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988172/
https://ncbi.nlm.nih.gov/pubmed/30018964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000481400
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