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Interferon γ receptor downregulation facilitates Legionella survival in alveolar macrophages

Legionella pneumophila is an opportunistic human pathogen and causative agent of the acute pneumonia known as Legionnaire’s Disease. Upon inhalation, the bacteria replicate in alveolar macrophages (AM), within an intracellular vacuole termed the Legionella containing vacuole. We recently found that,...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Yang, Chao, McDermot, Daniel S., Pasricha, Shivani, Bedoui, Sammy, Lenz, Laurel L., van Driel, Ian R., Hartland, Elizabeth L.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015206/
https://ncbi.nlm.nih.gov/pubmed/31793076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4MA1019-152R
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