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Reduced production of interleukin 12 by interferon γ primed alveolar macrophages from atopic asthmatic subjects
BACKGROUND—Asthma is characterised pathologically by an inflammatory pulmonary infiltrate rich in T helper (Th) 2 cells and eosinophils. Interleukin (IL)-12 is a heterodimeric cytokine critical for driving the development of uncommitted Th cells to express a Th 1 phenotype. Reduced pulmonary product...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Group
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1745617/ https://ncbi.nlm.nih.gov/pubmed/10992536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.55.10.842 |
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