Loss of splicing factor IK impairs normal skeletal muscle development

BACKGROUND: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the molecular mechanism of IK has been previously reported in vitro, the physiological role of IK has not been fully understood in any animal model. Here, we generate an ik knock-o...

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Publicado en:BMC Biol
Autores principales: In Ka, Hye, Seo, Hyemin, Choi, Youngsook, Kim, Joohee, Cho, Mina, Choi, Seok-Yong, Park, Sujeong, Han, Sora, An, Jinsu, Chung, Hak Suk, Yang, Young, Kim, Min Jung
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015194/
https://ncbi.nlm.nih.gov/pubmed/33789631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-00980-y
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