Loss of splicing factor IK impairs normal skeletal muscle development

BACKGROUND: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the molecular mechanism of IK has been previously reported in vitro, the physiological role of IK has not been fully understood in any animal model. Here, we generate an ik knock-o...

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Pubblicato in:BMC Biol
Autori principali: In Ka, Hye, Seo, Hyemin, Choi, Youngsook, Kim, Joohee, Cho, Mina, Choi, Seok-Yong, Park, Sujeong, Han, Sora, An, Jinsu, Chung, Hak Suk, Yang, Young, Kim, Min Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8015194/
https://ncbi.nlm.nih.gov/pubmed/33789631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-00980-y
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