Inhibition of CXCR4 ameliorates hypoxia-induced pulmonary arterial hypertension in rats

Pulmonary vascular remodeling due to aberrant proliferation and migration of pulmonary artery smooth muscle cells (PASMCs) is the main characteristic of pulmonary arterial hypertension (PAH). CXCR4 is a specific stem cell surface receptor of cytokine CXCL12 which could regulate homing of hematopoiet...

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Publicat a:Am J Transl Res
Autors principals: Xu, Jingjing, Li, Xiangnan, Zhou, Siqi, Wang, Rui, Wu, Mengxi, Tan, Cheng, Chen, Jingyu, Wang, Zhiping
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2021
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014346/
https://ncbi.nlm.nih.gov/pubmed/33841670
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