Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition

BACKGROUND: Endothelial cells dysfunction is one of the hallmark pathogenic features of pulmonary arterial hypertension (PAH). Paeoniflorin (PF) is a monoterpene glycoside with endothelial protection, vasodilation, antifibrotic, anti–inflammatory and antioxidative properties. However, the effects of...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yu, Min, Peng, Liyao, Liu, Ping, Yang, Mingxia, Zhou, Hong, Ding, Yirui, Wang, Jingjing, Huang, Wen, Tan, Qi, Wang, Yanli, Xie, Weiping, Kong, Hui, Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090222/
https://ncbi.nlm.nih.gov/pubmed/32256050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S235207
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