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Spatial Genomic Analysis – a multiplexed transcriptional profiling method that reveals subpopulations of cells within intact tissues

Here we present Spatial Genomic Analysis (SGA), a quantitative single-cell transcriptional profiling method that takes advantage of single molecule imaging of individual transcripts for up to a hundred genes. SGA relies on a machine learning based image analysis pipeline that performs cell segmentat...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Lignell, Antti, Kerosuo, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8014251/
https://ncbi.nlm.nih.gov/pubmed/30194538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7651_2018_188
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