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Mutations in SARS‐CoV‐2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) RNA‐dependent RNA polymerase (RdRp) has been identified to be a mutation hot spot, with the P323L mutation being commonly observed in viral genomes isolated from North America. RdRp forms a complex with nonstructural proteins nsp7 and nsp8...

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Detalhes bibliográficos
Publicado no:J Med Virol
Main Authors: Reshamwala, Shamlan M. S., Likhite, Vishakha, Degani, Mariam S., Deb, Shalini S., Noronha, Santosh B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012999/
https://ncbi.nlm.nih.gov/pubmed/33433004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.26791
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