Circadian Rhythm Gene PER3 Negatively Regulates Stemness of Prostate Cancer Stem Cells via WNT/β-Catenin Signaling in Tumor Microenvironment

Prostate cancer (PCa) cells are heterogeneous, containing a variety of cancer cells with phenotypical and functional discrepancies in the tumor microenvironment, where prostate cancer stem cells (PCSCs) play a vital role in PCa development. Our earlier studies have shown that ALDH(hi)CD44(+) (DP) PC...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Li, Qilin, Xia, Ding, Wang, Zhihua, Liu, Bo, Zhang, Jing, Peng, Ping, Tang, Qiujun, Dong, Jie, Guo, Juan, Kuang, Dong, Chen, Weimin, Mao, Jing, Li, Qiuhui, Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012816/
https://ncbi.nlm.nih.gov/pubmed/33816508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.656981
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