Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

Bacteria respond to environmental changes by inducing transcription of some genes and repressing others. Sialic acids, which coat human cell surfaces, are a nutrient source for pathogenic and commensal bacteria. The Escherichia coli GntR-type transcriptional repressor, NanR, regulates sialic acid me...

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Publicado en:Nat Commun
Main Authors: Horne, Christopher R., Venugopal, Hariprasad, Panjikar, Santosh, Wood, David M., Henrickson, Amy, Brookes, Emre, North, Rachel A., Murphy, James M., Friemann, Rosmarie, Griffin, Michael D. W., Ramm, Georg, Demeler, Borries, Dobson, Renwick C. J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012715/
https://ncbi.nlm.nih.gov/pubmed/33790291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22253-6
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