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Sialic Acid-Mediated Gene Expression in Streptococcus pneumoniae and Role of NanR as a Transcriptional Activator of the nan Gene Cluster

In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39 to sialic acid (N-acetylneuraminic acid [Neu5Ac]). Transcriptome comparison of wild-type D39 grown in M17 medium with and without sialic acid revealed the elevated expression of various genes and operons, incl...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Afzal, Muhammad, Shafeeq, Sulman, Ahmed, Hifza, Kuipers, Oscar P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393437/
https://ncbi.nlm.nih.gov/pubmed/25724955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00499-15
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