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A novel proteomics approach to epigenetic profiling of circulating nucleosomes

Alteration of epigenetic modifications plays an important role in human cancer. Notably, the dysregulation of histone post-translational modifications (PTMs) has been associated with several cancers including colorectal cancer (CRC). However, the signature of histone PTMs on circulating nucleosomes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Van den Ackerveken, Priscilla, Lobbens, Alison, Turatsinze, Jean-Valery, Solis-Mezarino, Victor, Völker-Albert, Moritz, Imhof, Axel, Herzog, Marielle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012598/
https://ncbi.nlm.nih.gov/pubmed/33790358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86630-3
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