Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancer

The aim was to evaluate serum levels of circulating cell-free nucleosomes (ccfn) containing a variety of epigenetic signals including 5-methylcytosine DNA, histone modifications H3K9Me3, H3K9Ac, H3S10PO4, H3K36Me3, H4K20Me3, H4PanAc and pH2AX, nucleosome variant H2AZ and nucleosome adducts with HMGB...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Rasmussen, Louise, Christensen, Ib Jarle, Herzog, Marielle, Micallef, Jake, Nielsen, Hans Jørgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828191/
https://ncbi.nlm.nih.gov/pubmed/29535803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21908
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