Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis

Staphylococcus aureus is the predominant pathogen causing osteomyelitis. Unfortunately, no immunotherapy exists to treat these very challenging and costly infections despite decades of research, and numerous vaccine failures in clinical trials. This lack of success can partially be attributed to an...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Muthukrishnan, Gowrishankar, Wallimann, Alexandra, Rangel-Moreno, Javier, Bentley, Karen L. de Mesy, Hildebrand, Maria, Mys, Karen, Kenney, H. Mark, Sumrall, Eric T., Daiss, John L., Zeiter, Stephan, Richards, R. Geoff, Schwarz, Edward M., Moriarty, T. Fintan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012494/
https://ncbi.nlm.nih.gov/pubmed/33815412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.651515
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