A designer FG-Nup that reconstitutes the selective transport barrier of the nuclear pore complex

Nuclear Pore Complexes (NPCs) regulate bidirectional transport between the nucleus and the cytoplasm. Intrinsically disordered FG-Nups line the NPC lumen and form a selective barrier, where transport of most proteins is inhibited whereas specific transporter proteins freely pass. The mechanism under...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fragasso, Alessio, de Vries, Hendrik W., Andersson, John, van der Sluis, Eli O., van der Giessen, Erik, Dahlin, Andreas, Onck, Patrick R., Dekker, Cees
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012357/
https://ncbi.nlm.nih.gov/pubmed/33790297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22293-y
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