Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

AIMS/HYPOTHESIS: Oral administration of antigen can induce immunological tolerance. Insulin is a key autoantigen in childhood type 1 diabetes. Here, oral insulin was given as antigen-specific immunotherapy before the onset of autoimmunity in children from age 6 months to assess its safety and immune...

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發表在:Diabetologia
Main Authors: Assfalg, Robin, Knoop, Jan, Hoffman, Kristi L., Pfirrmann, Markus, Zapardiel-Gonzalo, Jose Maria, Hofelich, Anna, Eugster, Anne, Weigelt, Marc, Matzke, Claudia, Reinhardt, Julia, Fuchs, Yannick, Bunk, Melanie, Weiss, Andreas, Hippich, Markus, Halfter, Kathrin, Hauck, Stefanie M., Hasford, Jörg, Petrosino, Joseph F., Achenbach, Peter, Bonifacio, Ezio, Ziegler, Anette-Gabriele
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012335/
https://ncbi.nlm.nih.gov/pubmed/33515070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05376-1
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