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Antidepressant Effects and Mechanisms of Group II mGlu Receptor-Specific Negative Allosteric Modulators

In this issue of Neuron, Joffe et al. assess the antidepressant-relevant effects and underlying neural mechanisms of negative allosteric modulators selective for either metabotropic glutamate receptors 2 (mGlu(2)) or 3 (mGlu(3)). Negative modulation of both receptors enhanced excitatory glutamatergi...

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Bibliografske podrobnosti
izdano v:Neuron
Main Authors: Potter, Liam E., Zanos, Panos, Gould, Todd D.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011990/
https://ncbi.nlm.nih.gov/pubmed/31951525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.12.011
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