A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability

The endothelial cell barrier regulates the passage of fluid between the bloodstream and underlying tissues, and barrier function impairment exacerbates the severity of inflammatory insults. To understand how inflammation alters vessel permeability, we studied the effects of the proinflammatory cytok...

Full description

Saved in:
Bibliographic Details
Published in:Sci Signal
Main Authors: Maier-Begandt, Daniela, Comstra, H Skye, Molina, Samuel A, Krüger, Nenja, Ruddiman, Claire A, Chen, Yen Lin, Chen, Xiaobin, Biwer, Lauren A, Johnstone, Scott R, Lohman, Alexander, Good, Miranda E, DeLalio, Leon J, Hong, Kwangseok, Bacon, Hannah, Yan, Zhen, Sonkusare, Swapnil K, Koval, Michael, Isakson, Brant E
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011850/
https://ncbi.nlm.nih.gov/pubmed/33653920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aba2940
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items