A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability

The endothelial cell barrier regulates the passage of fluid between the bloodstream and underlying tissues, and barrier function impairment exacerbates the severity of inflammatory insults. To understand how inflammation alters vessel permeability, we studied the effects of the proinflammatory cytok...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Maier-Begandt, Daniela, Comstra, H Skye, Molina, Samuel A, Krüger, Nenja, Ruddiman, Claire A, Chen, Yen Lin, Chen, Xiaobin, Biwer, Lauren A, Johnstone, Scott R, Lohman, Alexander, Good, Miranda E, DeLalio, Leon J, Hong, Kwangseok, Bacon, Hannah, Yan, Zhen, Sonkusare, Swapnil K, Koval, Michael, Isakson, Brant E
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011850/
https://ncbi.nlm.nih.gov/pubmed/33653920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aba2940
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