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Dynamics of Hepatitis B virus capsid protein dimer regulate assembly through an allosteric network

While there is an effective vaccine for Human Hepatitis B Virus (HBV), 257 million people have chronic infections for which there is no cure. The assembly process for the viral capsid is a potential therapeutic target. In order to understand the capsid assembly process, we investigated the dimeric b...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Patterson, Angela, Zhao, Zhongchao, Waymire, Elizabeth, Zlotnick, Adam, Bothner, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011827/
https://ncbi.nlm.nih.gov/pubmed/32662972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00481
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