Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly

Hepadnaviruses are hepatotropic enveloped DNA viruses with an icosahedral capsid. Hepatitis B virus (HBV) causes chronic infection in an estimated 240 million people; woodchuck hepatitis virus (WHV), an HBV homologue, has been an important model system for drug development. The dimeric capsid protei...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Zhao, Zhongchao, Wang, Joseph Che-Yen, Gonzalez-Gutierrez, Giovanni, Venkatakrishnan, Balasubramanian, Asor, Roi, Khaykelson, Daniel, Raviv, Uri, Zlotnick, Adam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Structure and Assembly
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600186/
https://ncbi.nlm.nih.gov/pubmed/31043524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00141-19
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