Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly

Hepadnaviruses are hepatotropic enveloped DNA viruses with an icosahedral capsid. Hepatitis B virus (HBV) causes chronic infection in an estimated 240 million people; woodchuck hepatitis virus (WHV), an HBV homologue, has been an important model system for drug development. The dimeric capsid protei...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Zhao, Zhongchao, Wang, Joseph Che-Yen, Gonzalez-Gutierrez, Giovanni, Venkatakrishnan, Balasubramanian, Asor, Roi, Khaykelson, Daniel, Raviv, Uri, Zlotnick, Adam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Structure and Assembly
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600186/
https://ncbi.nlm.nih.gov/pubmed/31043524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00141-19
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