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The haplolethality paradox of the wupA gene in Drosophila
Haplolethals (HL) are regions of diploid genomes that in one dose are fatal for the organism. Their biological meaning is obscure because heterozygous loss-of-function mutations result in dominant lethality (DL) and, consequently, should be under strong negative selection. We report an in depth stud...
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| Vydáno v: | PLoS Genet |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011728/ https://ncbi.nlm.nih.gov/pubmed/33739971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009108 |
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